National Register Listing

Main-Spanish Commercial Historic District

Roughly the 100 blocks of Main and Spanish Sts. and adjacent portions of Themis and Independence, Cape Girardeau, MO
Local significance of the district:
Architecture; Commerce

Listed in National Register of Historic Places in 2008.

The National Register of Historic Places is the official list of the Nation’s historic places worthy of preservation. Authorized by the National Historic Preservation Act of 1966, the National Park Service’s National Register of Historic Places is part of a national program to coordinate and support public and private efforts to identify, evaluate, and protect America’s historic and archeological resources.