Native Americans at the River

Historical marker location:

1600 Twigg Street, Palatka, Florida

( Marker can be reached from Twigg Street east of South 18th Street, on the right when traveling east.)

5000 BC to 1842.

The Spanish established the first mission in Florida, Mission San Luis de Apalachee, in 1633. The mission was located near present-day Tallahassee and was home to a large Native American population.