Explore Southwest Florida Naturally!

Historical marker location:

10901 Palm Beach Blvd, Fort Myers, Florida

( Marker can be reached from Palm Beach Boulevard (State Road 80) 1.5 miles east of Interstate 75, on the right when traveling east.)

The Spanish established the first mission in Florida, Mission San Luis de Apalachee, in 1633. The mission was located near present-day Tallahassee and was home to a large Native American population.